Chemotherapy Treatment of Advanced Liver Cancer

There are only a handful of liver cancer chemotherapy options for patients.  There are ongoing studies, however, that will hopefully provide more treatment options.

The most common chemotherapy drugs for treating liver cancer include:

  • Gemcitabine (Gemzar)
  • Oxaliplatin (Eloxatin)
  • Cisplatin
  • Doxorubicin (pegylated liposomal doxorubicin)
  • 5-fluorouracil (5-FU)
  • Capecitabine (Xeloda)
  • Mitoxantrone (Novantrone)


Sometimes, combinations of several drugs are used. GEMOX (gemcitabine plus oxaliplatin) is one option and FOLFOX is another.

Chemotherapy can also be used in combination with immuno-oncology or immunotherapy.  Targeted procedures may also be an option.